Alt image Alt image Alt image

Sleep-Aid Microneedle Patch

In CtrolRLS™ Transdermal Controlled-Release Technology
15-Minute Fast Fall Asleep
8-hour full-cycle sleep support

Get a Quick Quote

OEM/ODM Melatonin Microneedle Sleep Patches | Transdermal Sleep Aid Manufacturer

Title

Revolutionize Your Wellness Line with High-Absorption Sleep Technology Offer your customers a superior alternative to oral supplements. Our Dissolving Microneedle Sleep Patches bypass the digestive system to deliver Melatonin and GABA directly into the bloodstream. This transdermal delivery system ensures faster onset and higher bioavailability than gummies or pills, helping users fall asleep faster without the "morning grogginess."

Why Microneedles Outperform Traditional Sleep Aids

Superior Bioavailability: Bypasses first-pass metabolism (digestion) for up to 90% absorption rate.

Fast-Acting Relief: Microdarts dissolve and release active ingredients within 30 minutes to induce rapid sleep onset.

Sustained Release: Designed to release ingredients steadily through the night to prevent waking up midway.

Clean & Natural: Formulated with Melatonin, GABA, Valerian Root, and Lavender—non-habit forming and safe for daily use.

Custom Sleep Solutions for Global Brands We provide end-to-end manufacturing services for supplement and skincare brands.

Private Label: Custom packaging design and logo placement with low MOQ.

Formula Customization: Adjust Melatonin dosage or add ingredients like Magnesium or L-Theanine.

Global Compliance: Manufactured in ISO-certified facilities; documentation support for FDA/EU export.

Applications: Ideal for travel wellness (jet lag), insomnia relief, and natural health product lines.

Title

Contact Us

Clinically-Validated Efficient Delivery

Verified by Confocal Raman Spectroscopy on human skin, showing significantly enhanced penetration vs. topical application:

  • 4.17× higher absorption for small molecules
    (VC Ethyl Ether, 204 Da)
  • 10.66× higher absorption for medium-sized molecules
    (Madecassoside, 975 Da)
  • 98.69× higher absorption for large molecules
    (Growth Factors, 22 kDa)

One-Step LT-MN Technology

Proprietary patented rapid low-temperature microneedle forming technology that preserves active stability and ensures consistent manufacturing quality.

  • Molding: 30–60 min
  • Needle strength: >0.3N
  • Curing: 4–26°C for activity preservation
  • Yield: >98%
  • Patents: 100+

Modular Skin Patch Design Platform

Enabling formulation adaptability, skin compatibility, and flexible treatment-oriented product formats.

  • Shapes: Round, oval, strip, square, or custom geometries
  • Colors: Transparent, skin-tone, white, or brand-matched
  • Microneedle Length: 270 μm | 450 μm options
  • Materials: Dissolving polymers, hydrocolloid systems
  • Patch Sizes: Fully customizable, with no practical size limitation

Product Specifications

Title

Needle Length: 270 µm

Active Ingredients: Melatonin, GABA, VB6, Passionflower, Valerian, Ziziphus, Sour Cherry

Number of Microneedles: ~140

Recommended Usage Time: ~8 hours (overnight)

Quantity per Pack: 9 Patches

FAQ

Does melatonin have side effects?

• Exogenous melatonin is chemically identical to endogenous melatonin
• Naturally metabolized with short half-life, minimal accumulation
• Clinical studies: long-term use (2 years, 5mg/day) showed no adverse effects

How does patch bioavailability compare to oral melatonin?

• 8.5× higher than oral administration

How does the patch work?

• In CtrolRLS® controlled-release microneedle technology delivers melatonin and sleep-promoting ingredients via the skin within 30 min
• Sustained release supports deep, uninterrupted sleep overnight

Why might the patch not work?

• Designed for users with circadian rhythm disruption (jet lag, irregular schedule, night shifts, older adults)
• Use according to sleep severity (mild, moderate, severe)
• Correct application: press patch without air bubbles, ensure full dissolution
• Apply 30 min before sleep, reduce exposure to electronics and other stimulants

How long until it’s effective?

• Mild sleep issues: 1 patch improves sleep onset & reduces awakenings
• Moderate: 1–2 patches/day, improvements after 3 days
• Severe: 2–3 patches/day, improvements after 7 days

Sleep-Aid Microneedle Patch Introduction

Download Product PDF