Alt image Alt image Alt image

Sleep-Aid Microneedle Patch

In CtrolRLS™ Transdermal Controlled-Release Technology
15-Minute Fast Fall Asleep
8-hour full-cycle sleep support

Get a Quick Quote

OEM/ODM Dissolving Microneedle Sleep Patches

Title

Manufacturer for Fast-Acting & Non-Groggy Sleep Support


The Finest Transdermal Microneedle Delivery for Deep Sleep Care

The dissolving microneedle sleep patch delivers Melatonin and synergistic actives beneath the skin surface, bypassing digestion for faster onset and higher bioavailability than oral sleep aids. Designed to support rapid sleep initiation and sustained overnight release, it helps users fall asleep faster and wake up refreshed.

 

Next-Generation Alternative to Gummies & Capsules
Ideal for brands seeking high-performance, clean-label sleep solutions with strong differentiation in the wellness market.

 

Business Model
Private Label | Custom Formulation | OEM/ODM Manufacturing

Title

Contact Us

Clinically-Validated Efficient Delivery

Verified by Confocal Raman Spectroscopy on human skin, showing significantly enhanced penetration vs. topical application:

  • 4.17× higher absorption for small molecules
    (VC Ethyl Ether, 204 Da)
  • 10.66× higher absorption for medium-sized molecules
    (Madecassoside, 975 Da)
  • 98.69× higher absorption for large molecules
    (Growth Factors, 22 kDa)

One-Step LT-MN Technology

Proprietary patented rapid low-temperature microneedle forming technology that preserves active stability and ensures consistent manufacturing quality.

  • Molding: 30–60 min
  • Needle strength: >0.3N
  • Curing: 4–26°C for activity preservation
  • Yield: >98%
  • Patents: 100+

Modular Skin Patch Design Platform

Enabling formulation adaptability, skin compatibility, and flexible treatment-oriented product formats.

  • Shapes: Round, oval, strip, square, or custom geometries
  • Colors: Transparent, skin-tone, white, or brand-matched
  • Microneedle Length: 270 μm | 450 μm options
  • Materials: Dissolving polymers, hydrocolloid systems
  • Patch Sizes: Fully customizable, with no practical size limitation

Product Specifications

Title

Needle Length: 270 µm

Active Ingredients: Melatonin, GABA, VB6, Passionflower, Valerian, Ziziphus, Sour Cherry

Number of Microneedles: ~140

Recommended Usage Time: ~8 hours (overnight)

Quantity per Pack: 9 Patches

FAQ

Does melatonin have side effects?

• Exogenous melatonin is chemically identical to endogenous melatonin
• Naturally metabolized with short half-life, minimal accumulation
• Clinical studies: long-term use (2 years, 5mg/day) showed no adverse effects

How does patch bioavailability compare to oral melatonin?

• 8.5× higher than oral administration

How does the patch work?

• In CtrolRLS® controlled-release microneedle technology delivers melatonin and sleep-promoting ingredients via the skin within 30 min
• Sustained release supports deep, uninterrupted sleep overnight

Why might the patch not work?

• Designed for users with circadian rhythm disruption (jet lag, irregular schedule, night shifts, older adults)
• Use according to sleep severity (mild, moderate, severe)
• Correct application: press patch without air bubbles, ensure full dissolution
• Apply 30 min before sleep, reduce exposure to electronics and other stimulants

How long until it’s effective?

• Mild sleep issues: 1 patch improves sleep onset & reduces awakenings
• Moderate: 1–2 patches/day, improvements after 3 days
• Severe: 2–3 patches/day, improvements after 7 days

What makes this microneedle sleep patch different from other sleep aids?

This microneedle sleep patch features a science-backed dual-action formula that supports both fast sleep onset and sustained relaxation, rather than relying on a single sedative ingredient.

For rapid sleep induction, Melatonin + GABA + Vitamin B6 work synergistically to increase inhibitory neurotransmission and reduce brain excitability, helping you fall asleep faster.

For calm and sleep maintenance, Ziziphus Seed and Passionflower provide gentle, natural relaxation. Ziziphus is effective even under stimulants like caffeine and has shown improved sleep duration when combined with melatonin, while Passionflower is a GABA-rich, non-toxic calming botanical.

Sleep-Aid Microneedle Patch Introduction

Download Product PDF